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Visit One News Page for Italy news from around the world, aggregated from leading sources including newswires, newspapers and broadcast media. Search millions of archived news headlines. This feed provides the Italy news headlines.

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    Italy Deputy PM Di Maio says has full confidence in economy minister Italian Deputy Prime Minister and 5-Star Movement leader Luigi Di Maio said on Wednesday he had "full confidence" in Economy Minister Giovanni Tria after local media reports about Tria's possible resignation. ...... Reported by WorldNews 1 hour ago.

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    Keynotes, speakers and panels to examine the biggest trends and opportunities in the 10 sectors of the wellness economy—from tourism to food to fashion and more

    MIAMI (PRWEB) September 19, 2018

    The Global Wellness Summit (GWS), the foremost gathering of international leaders in the $3.7 trillion global wellness economy, today released the full agenda for its 2018 conference, taking place at Technogym Village in Cesena, Italy, this October 6–8.

    The theme of this year’s Summit is “Shaping the Business of Wellness,” and the three-day event is expected to attract over 600 business and thought leaders from 50 countries. The Summit is renowned for its keynotes and panels analyzing the largest opportunities unfolding in the wellness economy, from beauty and spa to fitness and fashion to workplace wellness, tourism and more.

    “Wellness is shaking up vast, consumer markets—in fact, it is beginning to touch almost every facet of our lives: where we live, when we travel, and where we work. The Global Wellness Summit is by far the most important international conference on the business of wellness,” said GWS CEO and Chair Susie Ellis. “The Summit represents an unprecedented opportunity for businesses, investors and government leaders to learn about today’s global wellness wave—and where it will go next.”

    Key Topics & Speakers

    Wellness Communities
    Wellness communities that put people’s health at the center of design are the next frontier in the fast-growing $134 billion residential real estate market. Italy has much to teach the world about healthy communities, from the Wellness Valley in the Emilia-Romagna region (where the Summit is being hosted) to Sardinia, Italy, which was identified as the original “Blue Zone” (places where people live the longest and are the healthiest). Best-selling author Dan Buettner, a world-renowned explorer and a writer for National Geographic who travels the world seeking out new Blue Zones, will present how these findings are informing new wellness community developments worldwide.

    Wellness Tourism, Spa & Thermal Springs
    A range of keynotes and presenters will explore where the hospitality, wellness travel and spa markets are heading, including a keynote by Rafat Ali, CEO of Skift, who will be speaking about the future of travel and overtourism in particular. Sir Rocco Forte, founder of Rocco Forte Hotels, will co-present with group project director and daughter, Irene Forte, and Sue Harmsworth MBE, founder of ESPA International, will interview a panel of top experts on what’s working—and not—in luxury hospitality, spa and wellness.

    The Future of Preventative Health
    The latest in preventative health approaches will be a central topic at the conference, with keynotes from leading medical experts, including Ranieri Guerra, MD, the current World Health Organization assistant director general for strategic initiatives; Dr. Richard H. Carmona, the 17th surgeon general of the US; Sergio Pecorelli, MD, OBGYN, surgeon, researcher and chancellor emeritus at the University of Brescia and former president of the Italian FDA; and KPMG International’s Mark Britnell, global chairman and senior partner, infrastructure, government and healthcare.

    Food, Beverage & Healthy Eating
    How wellness is disrupting the food and beverage markets will be examined in keynotes by experts, such as Andrea Illy, chairman of Italy’s coffee powerhouse, illycaffè; Mindy Grossman, president and CEO of global weight loss-turned-wellness brand, Weight Watchers; and Neil Grimmer, founder of Habit, the world’s first personalized nutrition company.

    Architecture, Design & Retail
    Italy is known as “Design Central,” and the ways that wellness concepts are remaking retail, design and architecture will be a hot topic examined in high-profile keynotes, such as those from famed Italian fashion designer Alberta Ferretti, award-winning Italian architects Antonio Citterio and Matteo Thun, and pioneering wellness designer Clodagh. Dr. Anjan Chatterjee, chair of neurology at Pennsylvania Hospital and author of The Aesthetic Brain, will present new research in his keynote on “Buildings, Beauty, and the Brain: A Neuroscience of Architectural Experience.”

    Fitness & Mind-Body
    The future of the $542 billion fitness and mind-body sector will be explored in keynotes from industry giants, such as Nerio Alessandri, founder of Italy-based Technogym, a world leader in fitness technologies. With a mounting global depression and anxiety epidemic, the need for new approaches in mental wellness will also be on the agenda, including a keynote from Bob Roth, CEO of the David Lynch Foundation and author of the new best seller, Strength in Stillness: The Power of Transcendental Meditation. Well+Good founder Melisse Gelula’s keynote will address America’s obsession with CBD, the cannabis- and hemp-derived ingredient whose popularity is soaring in the US; and a white paper “Mental Wellness: Pathways, Evidence and Horizons” will be released.

    Beauty, Wellness and Retail
    The $1 trillion beauty market is being reshaped by wellness. LS:N Global, The Future Laboratory, one of the world’s leading forecasting firms, will be identifying the disruptive beauty trends on the horizon. Roundtables will investigate the future of wellness and retail, and Dave McCaughan, chief strategy officer at Ai.Agency, will share how artificial intelligence will dramatically impact both wellness and retail.

    Delegates will mix the business of wellness with the pleasure of it, as the 2018 Summit takes place in a unique location called the Wellness Valley, an area between the Adriatic coast and the hills of Emilia-Romagna. In addition, when not in sessions, delegates can choose from wellness activities, such as Dance Energy Breaks sponsored by the Center for Transformative Movement and Wellness Walks on the Beach hosted by Weight Watchers. The conference will also host the first-ever “Wellness Meets Fashion” runway show, brought to life by Jessica Jesse, CEO and creative director of BuDhaGirl.

    The 2018 Global Wellness Summit is close to being sold out. Interested parties should apply to attend immediately.

    About the Global Wellness Summit: The Global Wellness Summit is an invitation-only international gathering that brings together leaders and visionaries to positively shape the future of the $3.7 trillion global wellness economy. Held in a different location each year, Summits have taken place in the US, Switzerland, Turkey, Bali, India, Morocco, Mexico and Austria. The 12th-annual Summit will be held at Technogym Village, Cesena, Italy, from October 6–8, 2018. Reported by PRWeb 1 hour ago.

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    Italy's populist ruling coalition called on Economy Minister Giovanni Tria on Wednesday to allow greater deficit spending in next year's budget in order to make good on campaign promises, causing jitters in financial markets worried about debt. Reported by DNA 55 minutes ago.

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    Italy’s bid for the 2026 Winter Olympic has one less city following Turin's exclusion. Italy will now present a joint bid involving the two northern cities of Milan and Cortina d’Ampezzo. Reported by euronews 46 minutes ago.

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    Addition to Panini Executive Leadership Team

    DAYTON, Ohio, Sept. 19, 2018 (GLOBE NEWSWIRE) -- Panini is pleased to announce that effective September 17, 2018, Dan Napoles joined the company as Senior Vice President, Global Technical Services (GTS) and will lead the company’s technical services functions worldwide including services delivery, services program definition & development, GTS commercial results & operational excellence, and GTS strategic direction & growth. Napoles will be instrumental to Panini’s strategy to support continued growth while extending its market leadership position.Mr. Napoles comes to Panini after a highly successful career in services with Avery Dennison, a $6.6 billion global materials science and manufacturing company with operations in more than 50 countries.  During his tenure with Avery Dennison, Dan started as a field engineer in Los Angeles CA, servicing printers and radio frequency security systems, including system installation and contract sales responsibilities. He was promoted to Services Branch Manager where he managed a team of field service engineers and depot technicians. Dan was responsible for all branch operations, and in this role, Dan achieved dramatic business growth.  He was then promoted to US Central Region Services Director, managing an extensive team of field engineers, major depot/repair centers and a pre-print center.  He continued to demonstrate his capacity for maximizing customer satisfaction and business results, and based on Dan’s outstanding performance in the field, he was promoted to a corporate position responsible for all service operations administration for North American, South American, and Western European markets. By applying his first-hand field services expertise, Dan reengineered all aspects of service operations. His extensive experience in all aspects of global technical services is a tremendously valuable addition to the Panini team and a strong statement regarding Panini’s commitment to world-class service and support.

    Dan earned a Bachelor of Arts Degree in Business Management with honors from Capital University. He also completed an intensive executive services program at Oracle University Training Center.

    “I’m delighted to add Dan’s talents, experience and enthusiasm to our team,” says Michael Pratt, CEO, Panini. “The addition of a senior executive of this caliber will be instrumental to our continued expansion while reinforcing our commitment to global service excellence.”

    *About Panini *
    Founded in Turin, Italy, Panini has enabled clients to capitalize on shifts in the global payments processing market for over seventy years.  Panini has a rich history of technology innovation, leveraging the company’s expertise in research & development. Panini’s market leading solutions are based on state-of-the-art engineering resources and ISO 9001 quality certified production. Panini offers check capture platforms which enable customers to fully realize the advantages and efficiencies available with the digital transformation of the paper check, resulting in the world’s largest deployed base of check capture systems, now exceeding one million devices. Panini’s scalable solutions address the complete range of distributed check processing opportunities including teller capture, back-counter capture, remote deposit capture, check cashing and remittance processing and point-of-sale capture. The company operates on a global scale and has direct subsidiaries in the United States covering North America and in Brazil covering Latin American markets.
    For more information visit www.panini.com.

    Jessica Back, Communications
    jess.back@panini.com
    +1 937.291.2195 Reported by GlobeNewswire 38 minutes ago.

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    Silversea Cruises continues to bring innovation to the luxury travel industry with a remarkable collection of 191 stunning new voyages.

    MONACO (PRWEB) September 19, 2018

    Industry-leading Silversea Cruises opens pre-sale bookings to Venetian Society members for 191 stunning new voyages, which will set sail between summer 2020 and winter 2021. With unprecedented variety and incorporating the launch of Silver Moon, the new collection of itineraries will take guests to 572 destinations in 84 countries and promises to unlock an innumerable range of deep travel experiences in all seven continents. While the pre-sale for Silversea’s Venetian Society members will enable past guests to make reservations before all others, bookings for the new itineraries will open to the general public on October 1, 2018.

    A highlight of the new itinerary collection, Silversea’s Silver Moon will set sail on her inaugural voyage on August 6, 2020: the ship will depart Trieste, Italy, for Civitavecchia on an 11-day cruise. The sister ship of Silversea’s flagship, Silver Muse, Silver Moon will benefit from a number of onboard enhancements. One of five Silversea ships in the region in the summer of 2020, she will cruise in the Mediterranean for her maiden season, until November, when she will cross the Atlantic to Fort Lauderdale.    

    From the ships in each region to the choice of itineraries on offer, Silversea’s guests will enjoy a more diverse range of options than ever before. As well as five ships and 54 voyages in the Mediterranean - including a 37-day, 28-port grand voyage - guests will be able to choose from four ships and 29 voyages in Northern Europe; three ships and 21 voyages in Alaska and the Russian Far East; and two ships and 10 voyages in the Arctic, among voyages in many other appealing regions. Plus, guests will enjoy more overnights than ever before, enabling them to unlock more deep travel experiences in the most amazing destinations around the world. Every voyage over seven nights in Europe and Canada & New England will benefit from an overnight in strategically selected ports.

    The new collection of itineraries will incorporate a remarkable polar programme, comprising 10 itineraries and 83 destinations in the Arctic and 11 itineraries and 26 destinations in Antarctica, including East Antarctica and the Ross Sea. Unprecedented voyages to New Zealand’s sub-Antarctic islands and Australia’s Macquarie Island (all UNESCO World Heritage Sites) will enable guests to view vast colonies of penguins and thousands of seals; visits to Churchill and Hudson Bay in Manitoba, Canada, will take guests to the ‘polar bear capital of the world’ and the home of world’s largest beluga whale population, respectively; and concurrent crossings of both the Northwest and Northeast Passages on Silver Cloud and Silver Explorer, respectively, will unlock unique, life-defining experiences with true expedition cruising at its most exhilarating.

    Silversea will bolster its already strong reputation as a destination-driven travel brand by enhancing its offering in a number of incredible destinations. In Iceland, for example, the cruise line will offer more immersive experiences on both classic and expedition voyages, with spectacular new itineraries. Departing June 29 from Reykjavik, Silver Wind will circumnavigate the island on a 9-day voyage. Other sample itineraries in Iceland include London to Reykjavik via Ireland and Reykjavik to London via Norway. As in 2019, the cruise line’s flagship, Silver Muse, will spend a full summer deployed in Alaska in 2020. Silversea will return to the Canary Islands on two voyages departing April 16 and September 25, 2020, and Istanbul on two different itineraries, departing May 30 and August 2, 2020. Moreover, the cruise line will make maiden calls in El Hierro, Spain; Fishguard, Wales; Nordfjordeid, Norway; Siglufjörður, Iceland; Durres, Albania; Klaksvik, Faroe Islands; and Patreksfjordur, Iceland.

    For the first time, Silversea guests will enjoy free economy-class air and transfers included as standard on all newly released voyages, simplifying the travel experience and enabling guests to discover the world with ease. Exceptions and market-specific conditions may apply.

    “We are extremely happy to open pre-sale exclusively to our valued Venetian Society members for our pioneering new itineraries,” says Barbara Muckermann, Silversea’s Chief Marketing Officer. “The variety of experiences on offer is unprecedented and unmatched; we are pushing the boundaries of ultra-luxury cruising for the benefit of our guests, enabling them to enjoy rare and authentic moments in the most fascinating corners of the world. With the launch of Silver Moon, our guests will experience the very best of Silversea’s industry-leading hospitality.”

    Browse Silversea’s new collection of voyages for summer 2020/winter 2021: https://www.silversea.com/2020-2021-new-itineraries.html

    Download images related to the new summer 2020/winter 2021 itineraries: https://www.dropbox.com/sh/380xtunhqc5mnva/AAAOOjTKDFWK5F1DtKDSKMg_a?dl=0 Reported by PRWeb 21 minutes ago.

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    SOLIDteknics USA may attract more chefs/cooks to use its new Chicago-made iron skillets as part of a movement away from synthetic nonstick pans due to health concerns, which are now being highlighted in the new movie The Devil We Know

    CHICAGO (PRWEB) September 19, 2018

    While SOLIDteknics USA’s new 12” US-ION™ wrought iron skillet has already raised nearly $100,000 as its crowdfunding campaign enters its final days on Kickstarter – presales may increase as chefs and cooks move away from synthetic nonstick pans with health warnings being raised in the upcoming movie The Devil We Know.

    “Our mission to replace synthetic and disposable cookware with new innovation in healthy, multi-century-durable lighter iron cookware really started about 10 years ago when I was researching cookware materials," said SOLIDteknics Founder Mark Henry. "I saw cooks were starting to understand the dangers, and they were looking for non-toxic cookware. That awareness really picked up momentum when over 200 scientists warned about synthetic pan coatings through their 2015 ‘Madrid Statement.'"

    In the 2015 statement, scientists from 38 countries warned about the dangers of PFAS chemicals used in manufacturing synthetic nonstick pans and other coated products, including 'modern convenience' products such as waterproof and spill-resistant coatings, takeaway food container coatings and nonstick cookware. The Madrid Statement cited data that links exposures to PFASs with certain cancers, delayed puberty, decreased fertility, reduced immune response in children and elevated cholesterol, among other health problems.

    The issues related to PFASs are highlighted in the new movie The Devil We Know, which relates the history of the first class-action lawsuit taken by a Virginia town against a company for exposing residents to the chemical. According to the movie’s website, as many as 110 million Americans may be drinking water tainted with PFAS chemicals -- with exposure to this class of chemicals becoming a global phenomenon spreading to other countries including Italy, the Netherlands and China.

    “Seasoned iron might not be quite as nonstick as the synthetic coatings, but when it is well-seasoned it is close, and it is all-natural, non-toxic, and forever renewable,” Henry said. “Our SOLIDteknics skillets and pans just get better with more cooking, just like seasoned cast iron, but our wrought iron pans are half the weight of cast iron. They will also last for centuries with a little care and are not disposable every few years like the synthetic nonsticks – making them more sustainable, which is something we care deeply about.”

    SOLIDteknics products are not cast, but wrought into shape through a new patented process – offering chefs half the weight of traditional cast iron while they season/cook with the same benefits. The cookware is the first to come with a multi-century warranty, since the tough wrought iron will never crack like cast iron – and there are no rivets or joints to fail over time.

    US-ION™ skillets are not only half the weight of regular cast-iron skillets, but being wrought iron also means the skillets are more conductive than cast iron, and also feature all the same healthy seasoning and cooking benefits as cast iron – without the arm strain.

    SOLIDteknics’ wrought iron skillets offer many benefits over other pans when cooking:·     Stainless steel is light, but too sticky for most types of frying.
    ·     Enamel cast iron really sticks when it’s worn, and it’s heavy.
    ·     Popular bare cast iron skillets cook great, and the natural seasoned nonstick you build yourself is non-toxic, but the pans are still heavy. Recent machined lighter cast iron pans are still relatively heavy, and susceptible to cracking.
    ·     French carbon steel pans are lighter, but come with rivets, and rivets mean gunk and eventually wobbly handles.
    ·     Ceramic coatings last about a year, then it’s another pan in the landfill.

    Also, any skillets with screws get jiggly – and cheap, carbon-steel woks inevitably fall apart. To eliminate that problem, the SOLIDteknics team developed a three-step method of forming a wrought pan from a single iron sheet, patented the method and started manufacturing AUS-ION skillets in Australia three years ago.

    The cookware quickly became popular with top chefs and home cooks and, with so much interest from American cooks, the company found a way to make the same pans in Chicago – using the same specification of iron used in Australia with the same patented method.

    The current campaign for a larger US-ION Skillet follows SOLIDteknics previous successful Kickstarter campaigns for its 7.5” and 10” US-ION™ skillets, which raised more than $311,000 from crowdfunders.

    For more information and to pre-order the skillet at an early-bird discount during crowdfunding, visit the 12-inch SOLIDteknics US-ION Campaign Page on Kickstarter. Limited ‘First Edition’ engraved US-ION™ 12” Skillets are still available for $89 and ‘Try Me’ 7.5” Skillets are $59 – significantly less than the recommended retail prices…..but not for long: the Kickstarter launch campaign ends within days. Reported by PRWeb 21 minutes ago.

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    SAN FRANCISCO, Sept. 19, 2018 (GLOBE NEWSWIRE) -- Hotwire, the global communications agency, today announced the expansion of its North American leadership team to support a rapidly growing B2B practice.Now leading the North American B2B practice as executive vice president is Heather Craft, formerly senior vice president of B2B at Hotwire. New hires Andrew Corcione, senior vice president and Keith Parker, vice president, will report to Craft.

    Craft has worked on some of the firm’s largest accounts including NetApp, Dell Boomi, Zuora and Commvault. Her expertise extends from IT and infrastructure to finance and cybersecurity. In this role, she is responsible for developing campaigns that support client business goals, client satisfaction for global and national accounts and for developing B2B talent at Hotwire.

    “In the competitive, constantly changing B2B market, it’s my job to help clients cut through the noise,” said Craft. “In this new role, I look forward to working with our global B2B organization to help Hotwire clients solve increasingly complicated problems, to enable our incredible staff do the work they love and of course, to deliver an exceptional client experience.”

    Corcione joins Hotwire from Finn Partners, where he was a partner and Next Tech Lead. He brings more than 17 years of experience across numerous engineering-based industries, including enterprise and consumer tech, artificial intelligence, artificial/virtual reality, auto tech and renewable energy. Corcione is responsible for driving the strategy and direction of the software and services clients in Hotwire’s B2B practice.

    Parker joins Hotwire from the Greater Sacramento Economic Council, where he served as the vice president of marketing and communications. Prior to that, he spent 10 years working abroad in both client-side and agency roles to deliver integrated communications campaigns. Parker will provide strategic council for some of the agency’s largest B2B accounts. 

    "Heather has been vital to the growth of our B2B practice in North America and an exceptional leader for our team. I am confident our clients and team will benefit from her expertise and leadership,” said Heather Kernahan, president of Hotwire North America. “We’re also excited to have new talent join us. Our mission is to be the best agency you’ll ever work with and that means hiring the best talent. Andrew and Keith bring global perspective and deep tech experience and will have an immediate impact on our clients.”

    *Notes to editors **
    *For more information, please email christine.penwell@hotwireglobal.com

    *About Hotwire**
    *Hotwire, the global communications agency, helps CMOs better engage and connect with their customers. From Sydney to San Francisco, we operate with a borderless mind-set across 22 locations including the UK, US, France, Germany, Spain, Italy and Australia, together with co-branded partners Yellow Communications in the Netherlands and Belgium, Active DMC in the Middle East and VIANEWS in Brazil, as well as other affiliate partners. For more information, please visit www.hotwireglobal.com.

    *About Enero*
    Hotwire is wholly owned by Enero Group Limited, a company listed on the Australian Securities Exchange (ASX:EGG). The Enero Group is a boutique network of marketing and communications businesses that includes BMF, CPR, Frank PR, Hotwire, Naked Communications, OB Media, Precinct, Orchard Marketing, The Digital Edge and The Leading Edge. For more information, please visit www.enero.com. Reported by GlobeNewswire 19 minutes ago.

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    Reported by newKerala.com 1 hour ago.

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    According to various reports in Italy, Francesco Totti has revealed that he was once tempted by a move to Real Madrid after he was sent a Real shirt with his name on it in an attempt to lure him to the Bernabeu. The Roma legend spent two decades carving out a tremendous career for himself […]

    The post Totti was ‘tempted’ by Real Madrid appeared first on Soccer News. Reported by SoccerNews.com 59 minutes ago.

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    Zaini Crockki Line begins shipping to U.S. Retailers Fall 2018

    ORANGE, Conn. (PRWEB) September 19, 2018

    PEZ Candy, Inc., today announced a distribution agreement with Luigi Zaini S.P.A. for licensed products in the United States. PEZ will begin distribution with the introduction of the Zaini Crockki brand.

    Zaini is an Italian confectionary producer established in 1913 in Milan, Italy. Four years ago the Zaini team collaborated with experts to develop a new product, with a limited quantity of sugars and saturated fats. The result, Zaini Crockki!

    Zaini Crockki is a fun way of snacking, that’s tasty, crispy and well balanced. Each selling unit includes a fun toy surprise, spoon, creamy hazelnut and cocoa spread with crispy cereal bites. With just 91 calories per portion and 5 grams of Sugar, Zaini Crockki is a delicious snack parents can feel good about sharing with their kids.

    The new Zaini Crockki line will launch in the U.S. with the iconic Smiley license. Additional licensing partners will follow to expand the line and meet the growing demand in the novelty chocolate category which has seen drastic growth in the last year with several new product introductions. Opening distribution for the Crockki line in the U.S. ensures consumers have a well-balanced alternative to the current category
    offerings.

    About Luigi Zaini S.P.A.:
    Zaini is an Italian confectionary producer established in 1913 in Milan. With more than 100 years of history and 3 production plans based in Milano Area, it produces sweet products of the best Italian handcraft tradition, together with innovation: Pralines, Chocolates, Dragées, Sugar-free product. On its portfolio, Zaini has also a dedicated line for children’s with collectable toys inside. Zaini products are available in more than 80 countries worldwide. To learn more visit http://www.zainispa.it

    About PEZ Candy, Inc.:
    Based in Orange, CT, PEZ has been inspiring and innovating since 1927. PEZ Candy, Inc. is the pioneer of interactive candy that is both enjoyable to eat and fun to play with. PEZ was first marketed as a compressed peppermint candy in 1927 in Vienna, Austria. Today, the company sells and markets its products worldwide with locations in Orange, Connecticut and Traun, Austria. Between them, the two locations distribute approximately 70 million dispensers and 5 billion candies per year. PEZ products are available in more than 80 countries worldwide and are a hot collectible for adults and children alike. PEZ dispensers have been a staple of American pop culture for over 60 years. To learn more, visit us.pez.com. Reported by PRWeb 49 minutes ago.

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    Italian agricultural group Coldirett also blamed UK food labelling systems for decline in popularity Reported by Independent 5 hours ago.

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    Arsenal manager Unai Emery took to Twitter on Tuesday to wish the now former chief executive Ivan Gazidis all the best with his new job at AC Milan. Arsenal confirmed Gazidis’s departure to Italy early on Tuesday with a full statement by the Greek who ten years spent ten years. In his Tweet Emery thanked […] Reported by Football FanCast 5 hours ago.

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    Brendan Cole shows his posterior as he goes skinny dipping in Italy Ex-Strictly star Brendan Cole put on a cheeky display on Instagram on Monday, flashing his peachy posterior as he went skinny dipping in Italy. Reported by MailOnline 3 hours ago.

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    SAN FRANCISCO and TEL AVIV, Israel, Sept. 20, 2018 (GLOBE NEWSWIRE) -- Kalytera Therapeutics, Inc. (TSX VENTURE: KALY and OTCQB: KALTF) (the "*Company*" or "*Kalytera*") today provided an update on its lead product development program evaluating cannabidiol (“*CBD*”) for the prevention and treatment of acute graft versus host disease (“*GVHD*”).GVHD is a life-threatening complication commonly occurring after bone marrow transplant procedures. GVHD occurs when the transplanted donor cells attack the patient’s organs, including the skin, GI tract, liver, lungs, and eyes. GVHD is associated with acute and chronic illness, infections, disability, reduced quality of life, and death.

    It is estimated that up to 50% of patients who undergo a bone marrow transplant from a sibling donor, and up to 70% of patients who undergo a bone marrow transplant from an unrelated donor, will develop some level of GVHD. There are currently no FDA approved therapies for either the prevention or treatment of acute GVHD.

    CBD is a non-psychotropic ingredient of cannabis that does not cause euphoria or cognitive effects. The formulation of CBD that Kalytera is evaluating for the prevention and treatment of acute GVHD is a proprietary formulation that is designed to improve product stability and absorption after oral dosing. 

    *Kalytera’s Two Separate Programs in GVHD*

    The work that Kalytera is doing in GVHD consists of two separate product development programs: a program evaluating CBD for the prevention of acute GVHD; and a separate program evaluating CBD for the treatment of acute GVHD. Although there is some overlap between the two programs in terms of the data that will be required for FDA registration and marketing approval, the Phase 2 and Phase 3 clinical studies for each of these two programs will be separate and distinct.

    The Company’s program in prevention of acute GVHD is more advanced than is the program in treatment of acute GVHD. The prevention program is currently in Phase 2 clinical testing, with an ongoing study enrolling patients at three clinical sites in Israel. To expedite the enrollment process, Kalytera is expanding this study to include one additional site in Israel, and up to four additional sites in other jurisdictions, including Australia. Upon completion of this Phase 2 clinical study, the Company will begin preparations for the pivotal Phase 3 clinical study that will be required for approval.

    “We believe the best strategy for building shareholder value will be to advance our programs in GVHD to Phase 3 status. We will be able to initiate the Phase 3 pivotal registration study in prevention of acute GVHD ahead of the Phase 3 study in treatment of acute GVHD, and, for this reason, we will prioritize the program in prevention of acute GVHD over the companion program in treatment of acute GVHD,” said Robert Farrell, President and CEO of Kalytera. “We expect to initiate the Phase 3 clinical study in prevention of acute GVHD within the next 12 months. Our plans for this program are as follows: (1) we plan to announce interim data from the ongoing Phase 2 study later this year; (2) we will complete the Phase 2 study in Q2 2019; and (3) we plan to initiate the Phase 3 clinical study during Q3 2019. We have also begun the process of seeking corporate partnering opportunities for both of our GVHD programs. The objective of such a partnership will be to provide a non-dilutive source of funding for the programs, as well as future revenue through licensing fees, milestone payments and royalties.”

    Prior to the ongoing Phase 2 clinical study in prevention of acute GVHD, two Phase 2a clinical studies were completed evaluating CBD in the prevention of GVHD. Data from both of these clinical studies were positive and highly encouraging. Dr. Moshe Yeshurun, Kalytera’s Chief Medical Officer, was the Principal Investigator for both of these studies, which were conducted at the Institute of Hematology, Davidoff Center, Rabin Medical Center, Petah Tikva, Israel. These studies were carried out by Dr. Yeshurun prior to the date he joined the Company, and the Company subsequently acquired the relevant technology through its acquisition of Talent Biotechs Ltd. in February 2017.

    The results from the first of these clinical studies were published in Biology of Blood and Marrow Transplantation (Cannabidiol for the Prevention of Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study, M. Yeshurun et al. / Biology Blood Marrow Transplant 21 (2015) 1770 - 1775).

    As previously announced, the data from this study, in which 48 patients received daily doses of 150 mg of CBD administered twice daily for 7 days prior to the bone marrow transplant procedure and for 30 days after, demonstrated the following results:

    · No patients developed acute GVHD while being treated with CBD;
    · The rates of grades 2-4 acute GVHD by day 100 were 12.1%, compared with 46% in a group of all 101 hematopoietic stem cell transplant recipients who received standard GVHD prophylaxis at the same institution in Israel (the Institute of Hematology, Davidoff Center, Rabin Medical Center at Beilinson Hospital) directly prior to the onset of this study; and
    · CBD was found to be safe and well tolerated

    Kalytera also previously announced the results from the second of the two prior clinical studies, in which 12 patients were administered CBD at a dose of 150 mg administered twice daily from 7 days prior to the bone marrow transplant procedure until up to 100-days post transplantation. In that study, no safety issues were observed, and only 15% of patients in the CBD treatment group developed grades 2-4 acute GVHD, compared to a 46% incidence at the same institution in the historical group of 101 patients described above.

    On July 31, the Company met with the United States Food & Drug Administration (“FDA”). In accordance with the guidance received from the FDA, the Company plans to initiate two clinical studies in healthy volunteers this year. These studies will assess certain safety and laboratory parameters of CBD, including the effect of food intake on the absorption of oral CBD and the interaction of CBD with certain anti-fungal drugs. These studies will be conducted in parallel with the company’s ongoing Phase 2 clinical study in prevention of GVHD, and the data from these studies will be required by the FDA for both the Company’s prevention and treatment programs.

    “Acute GVHD is a severe complication of bone marrow transplant procedures that can lead to permanent impairment of quality of life and even death,” said Robert Farrell, President and CEO of Kalytera. “With no FDA approved therapy for the prevention of acute GVHD, there exists an important unmet medical need that we believe we can address. Based on the positive and encouraging results from the two prior Phase 2a clinical studies in prevention of GVHD, we are optimistic that our CBD product will address this unmet need, and will be demonstrated to be a safe and effective means to prevent the onset of acute GVHD.”

    The commercial opportunity for Kalytera’s CBD products for the prevention and treatment of GVHD is large. According to the January 2018 Market Forecast Report by DelveInsight Perspective, the potential market for a successful product for prevention and treatment of GVHD in the 7 major jurisdictions (the U.S., Germany, France, Italy, Spain, the U.K. and Japan) is estimated to be more than USD $408 million in 2018, and could grow to approximately USD $1.3 billion by 2027.

    If Kalytera’s CBD products are approved for the prevention and/or treatment of acute GVHD, the Company believes that, given the severe and life-threatening nature of this disorder, treating physicians would not be expected to prescribe anything other than the Company’s approved formulation of CBD (rather than non-approved CBD that might be available online or from other commercial sources).

    Kalytera is the exclusive licensee of two issued U.S. patents covering the use of CBD in the prevention and treatment of GVHD, and is also the exclusive licensee of pending patent applications in other jurisdictions for the use of CBD in the prevention and treatment of GVHD. In addition to these patents and patent applications, the Company has also obtained four orphan drug designations for the treatment and prevention of GVHD in the U.S. and Europe. Such orphan drug designations will provide 7-years of market exclusivity in the U.S., and 10-years of market exclusivity in the E.U., upon regulatory approval of the Company’s CBD products for the prevention and/or treatment of acute GVHD.

    The U.S. FDA has recommended that Kalytera apply for both Breakthrough Therapy and Fast Track Designations for our CBD products for prevention and treatment of acute GVHD, each of which could accelerate the approval process for these products.

    *About Kalytera Therapeutics*
    Kalytera Therapeutics, Inc. is pioneering the development of CBD therapeutics. Through its proven leadership, drug development expertise, and intellectual property portfolio, Kalytera seeks to establish a leading position in the development of CBD medicines for a range of important unmet medical needs, with an initial focus on GVHD and treatment of acute and chronic pain.

    · Website Home: https://kalytera.co/
    · News and Insights: https://kalytera.co/news/
    · Investors: https://kalytera.co/investors/

    *Cautionary Statements*
    Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

    This press release may contain certain forward-looking information and statements ("forward-looking information") within the meaning of applicable Canadian securities legislation, that are not based on historical fact, including without limitation in respect of its product candidate pipeline, planned clinical trials, regulatory approval prospects, intellectual property objectives and other statements containing the words "believes", "anticipates", "plans", "intends", "will", "should", "expects", "continue", "estimate", "forecasts" and other similar expressions. Readers are cautioned to not place undue reliance on forward-looking information. Actual results and developments may differ materially from those contemplated by these statements depending on, among other things, the risk that future clinical studies may not proceed as expected or may produce unfavourable results. Kalytera undertakes no obligation to comment on analyses, expectations or statements made by third parties, its securities, or financial or operating results (as applicable). Although Kalytera believes that the expectations reflected in forward-looking information in this press release are reasonable, such forward-looking information has been based on expectations, factors and assumptions concerning future events which may prove to be inaccurate and are subject to numerous risks and uncertainties, certain of which are beyond Kalytera's control. The forward-looking information contained in this press release is expressly qualified by this cautionary statement and is made as of the date hereof. Kalytera disclaims any intention and has no obligation or responsibility, except as required by law, to update or revise any forward-looking information, whether as a result of new information, future events or otherwise.

    *Contact Information*

    · Robert Farrell
    President, CEO
    (888) 861-2008
    info@kalytera.co Reported by GlobeNewswire 3 hours ago.

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    Dublin, Sept. 20, 2018 (GLOBE NEWSWIRE) -- The "BIPV Market Forecast and Analysis 2018-2027" report has been added to *ResearchAndMarkets.com's* offering.This report provides a detailed worldwide BIPV market forecast in ten-year terms in both revenue ($ Millions) and volume (MW) terms. The report analyzes the demand for BIPV in 13 different nations/regions worldwide and examines how the BIPV supply structure is evolving.*BIPV roofing, walling and glass are covered in this report, which also includes:*

    An assessment of how much of the BIPV market is met by standard solar panels throughout the forecasting period and how much will consist of BIPV-specific products. In the future, how much of the BIPV business will remain in the hands of local developers, builders and architects and how much will shift to brand name BIPV-specific products?

    A breakdown of BIPV purchases over the next ten years by type of building. Buildings covered in this analysis include: government-owned offices; corporate HQs; schools, universities and libraries; hospitals and clinics; hotels and motels; airports, train stations, etc.; multi-tenant buildings; multi-tenant units; luxury homes; factories and warehouses

    A discussion of the impact of the worldwide reduction in subsidies for BIPV. How much will the resulting decline in demand for BIPV be compensated for by near-zero buildings and solar mandates? Can mandates replace incentive?

    A future technology assessment for BIPV. Can OPV and thin-film PV make a comeback for BIPV? Will improved manufacturing processes help to bring down the cost of BIPV panels? If BIPV doesn't return to being a technology play, then can integration of BIPV into variety of building products such as windows, tiles, and walls make money for innovative product designs?

    Throughout this BIPV market forecast report, we discuss how demand patterns for BIPV are evolving and how these are also changing marketing requirements and business development strategies for BIPV. We also discuss the business strategies of the leading (and most interesting) firms in the BIPV space. The publisher has a decade of experience covering the BIPV market and an insider knowledge of the market and its economic and technology drivers. All of this has helped compile this report as has our publications in several related fields, ranging from various next-generation PV technologies to related end markets including smart windows, smart coatings and smart surfaces.

    *Key Topics Covered:**Chapter One: Background to Report and Executive Summary*
    1.1 BIPV Market Evolution
    1.2 Growth by Building Type: Not Much Change Expected
    1.3 Whither BIPV Products and Technologies?
    1.4 What if BIPV is not about Technology?
    1.5 Objective and Scope of the Report
    1.6 Methodology of this Report
    1.7 Plan of this Report

    *Chapter Two: Products, Technologies and Suppliers for BIPV*
    2.1 Innovation in BIPV: Semantics and Technology
    2.2 The Future of BIPV Roofing
    2.2.1 CertainTeed: Saint-Gobain's BIPV Offering
    2.2.2 RGS: A Successor to Dow
    2.2.3 Forward Labs: Metal Roofs as BIPV
    2.2.4 Hanergy: CIGS BIPV Lives!
    2.3 Developments in BIPV Walling and Non-Standard Materials
    2.3.1 Heliatek: OPV for BIPV Walls?
    2.4 BIPV Glass: New Product Directions
    2.4.1 ISSOL and Solaxess
    2.4.2 Polysolar
    2.4.3 Vinci Construction
    2.4.4 Onyx Solar: An Established BIPV Firm
    2.4.5 Kawneer
    2.4.6 Sunpartner Technologies
    2.4.7 Redwood Renewables
    2.4.8 SunTegra (Formerly Integrated Solar Technology)
    2.4.9 Solaria

    *Chapter Three: Global Market Forecasts for BIPV*
    3.0 Introduction
    3.0.1 Some Notes on Europe
    3.1 China Now Dominates the BIPV Market
    3.2 BIPV Markets in the United States
    3.3 BIPV Markets in Japan
    3.4 BIPV Markets in Germany
    3.5 BIPV Markets in the U.K.
    3.6 BIPV Markets in Spain
    3.7 BIPV Markets in France
    3.8 BIPV Markets in Canada
    3.9 BIPV Markets in the MEA
    3.10 BIPV Markets in Mexico
    3.11 BIPV Markets in Italy
    3.12 BIPV Markets in Eastern Europe and Russia
    3.13 Some Notes and Forecasts of BIPV for IndiaFor more information about this report visit https://www.researchandmarkets.com/research/qp59z2/global_builtin?w=12

    Did you know that we also offer Custom Research? Visit our Custom Research page to learn more and schedule a meeting with our Custom Research Manager.

    CONTACT:
    CONTACT: ResearchAndMarkets.com
    Laura Wood, Senior Manager
    press@researchandmarkets.com
    For E.S.T Office Hours Call 1-917-300-0470
    For U.S./CAN Toll Free Call 1-800-526-8630
    For GMT Office Hours Call +353-1-416-8900
    Related Topics: Photovoltaics Reported by GlobeNewswire 3 hours ago.

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    Since both Italy and Malta have toughened their stances on migration, Spain has seen a surge in asylum seeker applications. Reported by euronews 3 hours ago.

    0 0

    The bridge was inspected following the deaths of 43 people when an earthquake brought down the Morandi bridge in Genoa in August. Reported by euronews 3 hours ago.

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    Italy’s populist coalition had been a source of concern since the March election, according to Tim Riddell, Research Analyst at Westpac.

    *Key Quotes*

    “Their first budget was expected to test EU budget responsibility amidst fears of a fiscal blowout due to the opposing stances of the rightwing League and spending-friendly 5 Star. Though still a risk, their budget appears to be falling well inside EU’s 3% deficit to GDP guidance and so a potential negative for EUR is turning into a supportive factor.”

    “Last week Draghi downplayed downside risks for a balanced and neutral outlook while maintaining their forward guidance. In addition to flash and Germany’s IFO survey, the ECB will be closely watching for any upside pressures within coming inflation data to offset external downside risks and persisting moderation in hard activity data.”

    “EUR/USD rebounds on the back of Italy’s reduced budget risk and consolidation in USD are likely to be short-term and capped within the current 1.12-1.19 range.” Reported by FXstreet.com 3 hours ago.

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    Join us in Anritsu’s Booth, #408

    SAN JOSE, Calif., Sept. 20, 2018 (GLOBE NEWSWIRE) -- eSilicon, a leading provider of FinFET-class ASICs, market-specific IP platforms and advanced 2.5D packaging solutions, will demonstrate the silicon performance of its 7nm 56G long-reach SerDes during ECOC in Rome, Italy on September 24-26.*What
    **7nm 56G long-reach SerDes demonstration
    *eSilicon will demonstrate the silicon performance of its 56G PAM4 SerDes by showing a periodic pattern generator (PPG)-to-chip live demo with different backplane reaches in the Anritsu Booth, #408. This is the first public demonstration of eSilicon’s 7nm SerDes technology showing one of its key features: high insertion loss tolerance with low bit-error rates to support increased bandwidth in legacy equipment.

    The demonstration will show 56G PAM4 data transfer running at 56Gb/s over two different BERTSCOPE channels with two different reaches, both driven by the Anritsu MP1900A Signal Quality Analyzer-R using a passive and an active PAM4 combiner. The demo with Anritsu is significant because it will show how it is possible to leverage TX finite impulse response (FIR) capabilities to increase performance and improve power figure of merit (FOM) and functionality.

    “To obtain such reach and effectively stress the PAM4 SerDes receiver, it is very important to be able to generate an original extremely high-quality signal, and include equalization and stress tools for full control of the TX side. During the bring-up period, a flexible solution like Anritsu’s MP1900A is the best choice for an interoperability test,” said Anritsu EMEA Wireline Marketing Director Alessandro Messina.

    *When*
    Monday-Wednesday, September 24-26, 2018

    *Where
    *ECOC Anritsu Booth, #408, Rome, Italy

    *About** ECOC
    *ECOC is the leading European conference in the field of optical communication.

    **About Anritsu Corporation*
    *Anritsu Corporation is a global provider of innovative communications test and measurement solutions for 120 years. Anritsu’s “2020 VISION” philosophy engages customers as true partners to help develop wireless, optical, microwave/RF, and digital solutions for R&D, manufacturing, installation, and maintenance applications, as well as multidimensional service assurance solutions for network monitoring and optimization. Anritsu also provides precision microwave/RF components, optical devices, and high-speed electrical devices for communication products and systems. The company develops advanced solutions for 5G, M2M, IoT, as well as other emerging and legacy wireline and wireless communication markets. With offices throughout the world, Anritsu has approximately 4,000 employees in over 90 countries.

    *About** e**Silicon**
    *eSilicon provides complex FinFET ASICs, market-specific IP platforms and advanced 2.5D packaging solutions. Our ASIC-proven, differentiating IP includes highly configurable 7nm 56G/112G SerDes plus networking-optimized 16/14/7nm FinFET IP platforms featuring HBM2 PHY, TCAM, specialized memory compilers and I/O libraries. Our neuASIC™ platform provides AI-specific IP and a modular design methodology to create adaptable, highly efficient AI ASICs. eSilicon serves the high-bandwidth networking, high-performance computing, artificial intelligence (AI) and 5G infrastructure markets. www.esilicon.com

    Collaborate. Differentiate. Win.

    eSilicon is a registered trademark, and the eSilicon logo and neuASIC are trademarks, of eSilicon Corporation. Other trademarks are the property of their respective owners.

     

    *Contacts:* * *
    Sally Slemons Susan Cain
    eSilicon Corporation Cain Communications
    408-635-6409 408-393-4794
    sslemons@esilicon.com  scain@caincom.com Reported by GlobeNewswire 3 hours ago.

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